An Apostolos Vellios goal was in vain as Nottingham Forest exited the Emirates FA Cup with a 2-1 defeat against Hull City.
The Reds hit the woodwork on two occasions but first-half Jarrod Bowen and Nouha Dicko goals were enough for the home side to earn their place in the fifth round.
Aitor Karanka was forced into one change to the side which defeated Wolves last weekend, with Mustapha Carayol coming in for the suspended Liam Bridcutt.
It was Carayol who had the game's first effort on goal on four minutes, with the winger finding himself in the centre of the pitch and hitting an effort which was always bending away from David Marshall's far post.
Despite that, the home side took control. A low free kick from Markus Henriksen was tipped wide of the post by Jordan Smith, and from the resulting corner it took some decisive action from the Forest stopper to smother at the feet of Bowen after Michael Hector's flick on.
Smith then created a problem in coming for a through ball which Joe Worrall appeared to have under control on 17 minutes, and the hesitation allowed Bowen to loop an effort over the stranded keeper but it bounced onto the post and into Smith's grateful hands.
But he wasn't so fortunate a minute later as Bowen gave Hull the lead. A swift break forward saw the wideman charge down the right and hit a shot goalwards which, after a deflection off Michael Mancienne, hit the inside of the post and went in.
The home side continued to come forward and the post gave The Tigers a big helping hand again on 40 as they doubled their lead. A cross to the back post found Dicko whose header beat Smith and hit the inside of the post before crossing the line.
Carayol had a great chance to immediately get The Reds back into the game on 43, but he could only divert his header wide of the post when well placed in front of goal as Forest went in 2-0 down at the break.
Karanka made a double change at the interval, bringing on David Vaughan and Zach Clough to try and change their fortunes, but it was Smith who was needed to deny the hosts a third on 52 as he tipped Dicko's low effort around the post.
The same post which aided Hull's efforts in the first half helped them out defensively this time, as Kieran Dowell's rasping free kick on 55 cannoned back of the goal frame and to safety with Marshall beaten.
A goalmouth scramble following a corner almost gave The Reds a route back into the game on 66 but the Hull defence managed to clear, and Marshall pulled off a fine save to deny Worrall's header from eight yards out on 76. Ben Brereton then flicked an effort onto the post, yet again, as the Hull goal led a charmed life as the pressure mounted.
Vellios came off the bench to add more firepower and it was the Greek striker who found the breakthrough for his first goal of the season on 88. A sumptuous delivery from the right by Matty Cash fell perfectly for Vellios in front of goal who showed no mercy in lashing the ball past Marshall.
But that was as far as the comeback went with the home side holding out to earn their spot in the fifth round of the Emirates FA Cup.
Forest: Smith, Lichaj, Worrall, Mancienne (c), Fox, Bouchalakis (Vaughan 46'), Osborn, Cash, Dowell, Carayol (Clough 46'), Brereton (Vellios 81')
Unused subs: Henderson, Mills, McKay, Darikwa
Bookings: Fox 25', Worrall 90'
Goal: Vellios 88'
Hull: Marshall (c), Aina, Mazuch, Hector, Clark, Henriksen, Stewart, Irvine (Batty 87'), Bowen, Diomande (Grosicki 71'), Dicko (Keane 62')
Unused subs: McGregor, Dawson, Campbell, Tomori
Goals: Bowen 18', Dicko 40'
Booking: Mazuch 90'
Referee: Stuart Atwell
Attendance: 13,450 (4,014 away)