The key midfielder sat out training yesterday as a precautionary measure after complaining of a tight calf muscle.
But O’Driscoll is confident Gillett will be declared fit to take his place in his starting line-up.
He told Forest Player: “We didn’t really want him to train because he has a knock.
“We’ll wait and see. There’s no indication at this stage that he will be a problem but you never know.
“Overnight things can sometimes clear up but sometimes it can make things worse. We kept him off his feet yesterday and he’s desperate to play.
“But he’s got to make that decision. We understand he wants to play but there’s no point playing at 80 per cent in this league, especially away from home where you have to be 100 per cent.”
O’Driscoll has confirmed that Dexter Blackstock and Jermaine Jenas will return to the squad for the trip to the Fylde coast.
Blackstock has missed the last three games through suspension, while Jenas wasn’t risked against Cardiff on Saturday after a back problem had limited his training.
Adlene Guedioura misses out as he starts a two-match ban following his sending-off against Cardiff.
Henri Lansbury and Marcus Tudgay got much-needed match minutes yesterday as they played for Forest’s Under 21 side against Wigan and both men are likely to make the trip to Blackpool.
Blackpool, meanwhile, look set to be without Craig Cathcart after he limped out of the warm-up ahead of their game against Burnley on Saturday.